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This code reflects harmful or hazardous use patterns (e.g., legal consequences, impaired functioning, risky behavior) without the hallmark features of dependence, such as loss of control, compulsive use, or prioritization of cannabis over other activities

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What we are seeing now with the explosive expansion of vaping products risks reversing decades of gains in reducing youth tobacco use, said Boston Board of Health Chairman Manny Lopes

Department of Health and Human Services (2004) Report on Carcinogens, 11th Edition